Ontology highlight
ABSTRACT:
SUBMITTER: Willie B
PROVIDER: S-EPMC4257894 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Willie B B Hall N B NB Stein C M CM Jurevic R J RJ Weinberg A A Mehlotra R K RK Zimmerman P A PA
Genes and immunity 20140925 8
Single-nucleotide polymorphisms (SNPs) in Toll-like receptor (TLR) genes TLR2-4 and TLR7-9, but not in TLR1 and TLR6, have been previously evaluated regarding human immunodeficiency virus (HIV) acquisition and disease progression in various populations, most of which were European. In this study, we examined associations between a total of 41 SNPs in 8 TLR genes (TLR1-4, TLR6-9) and HIV status in North American subjects (total n=276 (Caucasian, n=102; African American, n=150; other, n=24)). Stra ...[more]