Ontology highlight
ABSTRACT:
SUBMITTER: Maharaj AR
PROVIDER: S-EPMC4260000 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
CPT: pharmacometrics & systems pharmacology 20141022
Increased regulatory demands for pediatric drug development research have fostered interest in the use of modeling and simulation among industry and academia. Physiologically based pharmacokinetic (PBPK) modeling offers a unique modality to incorporate multiple levels of information to estimate age-specific pharmacokinetics. This tutorial will serve to provide the reader with a basic understanding of the procedural steps to developing a pediatric PBPK model and facilitate a discussion of the adv ...[more]