Ontology highlight
ABSTRACT:
SUBMITTER: Bhowmick M
PROVIDER: S-EPMC4260935 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Bhowmick Manishabrata M Fields Gregg B GB
Methods in molecular biology (Clifton, N.J.) 20130101
The triple-helical structure of collagen has been accurately reproduced in numerous chemical and recombinant model systems. Triple-helical peptides and proteins have found application for dissecting collagen-stabilizing forces, isolating receptor- and protein-binding sites in collagen, mechanistic examination of collagenolytic proteases, and development of novel biomaterials. Introduction of native-like sequences into triple-helical constructs can reduce the thermal stability of the triple-helix ...[more]