Primary intestinal and vertebral chordomas in laboratory zebrafish (Danio rerio).
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ABSTRACT:
SUBMITTER: Cooper TK
PROVIDER: S-EPMC4261063 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Publications
Primary intestinal and vertebral chordomas in laboratory zebrafish (Danio rerio).
Cooper T K TK Murray K N KN Spagnoli S S Spitsbergen J M JM
Veterinary pathology 20140609 2
Chordomas are uncommon neoplasms arising from notochord remnants, most commonly occurring in the axial skeleton. Extraskeletal soft tissue chordomas are rare primary tumors, and primary alimentary tract chordomas have not been reported. Herein we report 24 cases of spontaneous primary intestinal chordomas in zebrafish, as well as 9 spontaneous vertebral chordomas. Both intestinal and vertebral tumors showed invasive behavior, although more commonly in the latter. In all cases of primary intestin ...[more]
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