Ontology highlight
ABSTRACT:
SUBMITTER: Hua WY
PROVIDER: S-EPMC4263222 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Hua Wen-Yu WY Nichols Thomas E TE Ghosh Debashis D
Biostatistics (Oxford, England) 20140623 1
Recent research in neuroimaging has focused on assessing associations between genetic variants that are measured on a genomewide scale and brain imaging phenotypes. A large number of works in the area apply massively univariate analyses on a genomewide basis to find single nucleotide polymorphisms that influence brain structure. In this paper, we propose using various dimensionality reduction methods on both brain structural MRI scans and genomic data, motivated by the Alzheimer's Disease Neuroi ...[more]