Ontology highlight
ABSTRACT:
SUBMITTER: Chen L
PROVIDER: S-EPMC4263361 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Chen Lin L Noorbakhsh Javad J Adams Rhys M RM Samaniego-Evans Joseph J Agollah Germaine G Nevozhay Dmitry D Kuzdzal-Fick Jennie J Mehta Pankaj P Balázsi Gábor G
PLoS computational biology 20141211 12
Yeasts can form multicellular patterns as they expand on agar plates, a phenotype that requires a functional copy of the FLO11 gene. Although the biochemical and molecular requirements for such patterns have been examined, the mechanisms underlying their formation are not entirely clear. Here we develop quantitative methods to accurately characterize the size, shape, and surface patterns of yeast colonies for various combinations of agar and sugar concentrations. We combine these measurements wi ...[more]