Ontology highlight
ABSTRACT:
SUBMITTER: Piccirillo S
PROVIDER: S-EPMC6893387 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Piccirillo Sarah S McCune Abbigail H AH Dedert Samuel R SR Kempf Cassandra G CG Jimenez Brian B Solst Shane R SR Tiede-Lewis LeAnn M LM Honigberg Saul M SM
Genetics 20191016 4
Under conditions in which budding yeast form colonies and then undergo meiosis/sporulation, the resulting colonies are organized such that a sharply defined layer of meiotic cells overlays a layer of unsporulated cells termed "feeder cells." This differentiation pattern requires activation of both the Rlm1/cell-wall integrity pathway and the Rim101/alkaline-response pathway. In the current study, we analyzed the connection between these two signaling pathways in regulating colony development by ...[more]