Ontology highlight
ABSTRACT:
SUBMITTER: Khaldi N
PROVIDER: S-EPMC4264622 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Khaldi Nora N Vijayakumar Vaishnavi V Dallas David C DC Guerrero Andrés A Wickramasinghe Saumya S Smilowitz Jennifer T JT Medrano Juan F JF Lebrilla Carlito B CB Shields Denis C DC German J Bruce JB
Journal of agricultural and food chemistry 20140710 29
Human milk is known to contain several proteases, but little is known about whether these enzymes are active, which proteins they cleave, and their relative contribution to milk protein digestion in vivo. This study analyzed the mass spectrometry-identified protein fragments found in pooled human milk by comparing their cleavage sites with the enzyme specificity patterns of an array of enzymes. The results indicate that several enzymes are actively taking part in the digestion of human milk prot ...[more]