Ontology highlight
ABSTRACT:
SUBMITTER: Antony P
PROVIDER: S-EPMC4265431 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
BMC cancer 20141202
<h4>Background</h4>Posttranslational protein modifications are known to modulate key biological processes like proliferation and apoptosis. Accumulating evidence shows that ST6GAL1, an enzyme that catalyzes the transfer of sialic acid onto galactose-containing substrates, is aberrantly expressed in various cancers and may affect cell motility and invasion. This is the first study to describe ST6GAL1 expression and regulation in human bladder cancer.<h4>Methods</h4>ST6GAL1 mRNA expression levels ...[more]