Ontology highlight
ABSTRACT:
SUBMITTER: Perner J
PROVIDER: S-EPMC4267652 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Perner Juliane J Lasserre Julia J Kinkley Sarah S Vingron Martin M Chung Ho-Ryun HR
Nucleic acids research 20141120 22
Chromatin modifiers and histone modifications are components of a chromatin-signaling network involved in transcription and its regulation. The interactions between chromatin modifiers and histone modifications are often unknown, are based on the analysis of few genes or are studied in vitro. Here, we apply computational methods to recover interactions between chromatin modifiers and histone modifications from genome-wide ChIP-Seq data. These interactions provide a high-confidence backbone of th ...[more]