Ontology highlight
ABSTRACT:
SUBMITTER: Mitani Y
PROVIDER: S-EPMC4268116 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Mitani Yoshitsugu Y Rao Pulivarthi H PH Maity Sankar N SN Lee Yu-Chen YC Ferrarotto Renata R Post Julian C JC Licitra Lisa L Lippman Scott M SM Kies Merrill S MS Weber Randal S RS Caulin Carlos C Lin Sue-Hwa SH El-Naggar Adel K AK
Clinical cancer research : an official journal of the American Association for Cancer Research 20141014 24
<h4>Purpose</h4>To investigate the molecular events associated with the activation of androgen receptor (AR) as a potential therapeutic target in patients with salivary duct carcinoma (SDC).<h4>Experimental design</h4>Comprehensive molecular and expression analysis of the AR gene in 35 tumor specimens (20 males and 15 females) and cell lines derived from SDC using Western blotting and RT-PCR, FISH analysis, and DNA sequencing was conducted. In vitro and in vivo animal studies were also performed ...[more]