Ontology highlight
ABSTRACT:
SUBMITTER: Chae E
PROVIDER: S-EPMC4269942 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Chae Eunyoung E Bomblies Kirsten K Kim Sang-Tae ST Karelina Darya D Zaidem Maricris M Ossowski Stephan S Martín-Pizarro Carmen C Laitinen Roosa A E RA Rowan Beth A BA Tenenboim Hezi H Lechner Sarah S Demar Monika M Habring-Müller Anette A Lanz Christa C Rätsch Gunnar G Weigel Detlef D
Cell 20141120 6
Intraspecific genetic incompatibilities prevent the assembly of specific alleles into single genotypes and influence genome- and species-wide patterns of sequence variation. A common incompatibility in plants is hybrid necrosis, characterized by autoimmune responses due to epistatic interactions between natural genetic variants. By systematically testing thousands of F1 hybrids of Arabidopsis thaliana strains, we identified a small number of incompatibility hot spots in the genome, often in regi ...[more]