Modification of biomaterials with a self-protein inhibits the macrophage response.
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ABSTRACT:
SUBMITTER: Kim YK
PROVIDER: S-EPMC4272238 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
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Modification of biomaterials with a self-protein inhibits the macrophage response.
Kim Yoon Kyung YK Que Richard R Wang Szu-Wen SW Liu Wendy F WF
Advanced healthcare materials 20140220 7
A biomaterial inhibits the host immune response by displaying an endo-genously expressed immunomodulatory molecule, CD200. Immobilization of CD200 onto biomaterial surfaces effectively suppresses macrophage activation and reduces inflammatory response to subcutaneously implanted materials. ...[more]
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