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Deciphering laminar-specific neural inputs with line-scanning fMRI.


ABSTRACT: Using a line-scanning method during functional magnetic resonance imaging (fMRI), we obtained high temporal (50-ms) and spatial (50-?m) resolution information along the cortical thickness and showed that the laminar position of fMRI onset coincides with distinct neural inputs in rat somatosensory and motor cortices. This laminar-specific fMRI onset allowed us to identify the neural inputs underlying ipsilateral fMRI activation in the barrel cortex due to peripheral denervation-induced plasticity.

SUBMITTER: Yu X 

PROVIDER: S-EPMC4276040 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature

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Deciphering laminar-specific neural inputs with line-scanning fMRI.

Yu Xin X   Qian Chunqi C   Chen Der-yow DY   Dodd Stephen J SJ   Koretsky Alan P AP  

Nature methods 20131117 1


Using a line-scanning method during functional magnetic resonance imaging (fMRI), we obtained high temporal (50-ms) and spatial (50-μm) resolution information along the cortical thickness and showed that the laminar position of fMRI onset coincides with distinct neural inputs in rat somatosensory and motor cortices. This laminar-specific fMRI onset allowed us to identify the neural inputs underlying ipsilateral fMRI activation in the barrel cortex due to peripheral denervation-induced plasticity  ...[more]

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