Ontology highlight
ABSTRACT:
SUBMITTER: Mishel P
PROVIDER: S-EPMC4276832 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Mishel Polina P Bychkov Dmitrii D Kallio-Kokko Hannimari H Valkonen Miia M Kantele Anu A Mattila Pirkko P Almusa Henrikki H Jalovaara Petri P Kainov Denis D
Genome announcements 20141224 6
Here, we sequenced the genome of the influenza A/Finland/741 M/2014(H1N1) virus and found that the virus accumulated oseltamivir resistance mutation H275Y in its neuraminidase during propagation in cell culture. This indicates that propagation in cell culture modifies virus genomes. The instability of influenza genomes should be taken into consideration during drug-sensitivity studies. ...[more]