Ontology highlight
ABSTRACT:
SUBMITTER: Heckman MG
PROVIDER: S-EPMC4277668 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Heckman Michael G MG Schottlaender Lucia L Soto-Ortolaza Alexandra I AI Diehl Nancy N NN Rayaprolu Sruti S Ogaki Kotaro K Fujioka Shinsuke S Murray Melissa E ME Cheshire William P WP Uitti Ryan J RJ Wszolek Zbigniew K ZK Farrer Matthew J MJ Sailer Anna A Singleton Andrew B AB Chinnery Patrick F PF Keogh Michael J MJ Gentleman Steve M SM Holton Janice L JL Aoife Kiely K Mann David M A DM Al-Sarraj Safa S Troakes Claire C Dickson Dennis W DW Houlden Henry H Ross Owen A OA
Neurology 20141105 24
<h4>Objective</h4>The aim of this study was to evaluate the association between common exonic variants in the leucine-rich repeat kinase 2 (LRRK2) gene and risk of multiple system atrophy (MSA).<h4>Methods</h4>One series from the United States (92 patients with pathologically confirmed MSA, 416 controls) and a second series from the United Kingdom (85 patients with pathologically confirmed MSA, 352 controls) were included in this case-control study. We supplemented these data with those of 53 pa ...[more]