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Aptamer-based cell imaging reagents capable of fluorescence switching.

ABSTRACT: We describe an aptamer-conjugated polydiacetylene imaging probe (ACP) that shows highly specific fluorescence switching upon binding to epithelial cancer cells that overexpress the tumor biomarker protein EpCAM (epithelial cell adhesion molecule) on their surface.

SUBMITTER: Jung YK

PROVIDER: S-EPMC4277889 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature

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Aptamer-based cell imaging reagents capable of fluorescence switching.

Jung Yun Kyung YK Woo Min-Ah MA Soh H Tom HT Park Hyun Gyu HG

Chemical communications (Cambridge, England) 20141001 82

We describe an aptamer-conjugated polydiacetylene imaging probe (ACP) that shows highly specific fluorescence switching upon binding to epithelial cancer cells that overexpress the tumor biomarker protein EpCAM (epithelial cell adhesion molecule) on their surface. ...[more]

PMID: 25182171

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Nucleolin-aptamer therapy in retinoblastoma: molecular changes and mass spectrometry–based imaging

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Development of an efficient targeted cell-SELEX procedure for DNA aptamer reagents.

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Precise immuno-fluorescence canceling enables highly multiplexed imaging

Project description:This SuperSeries is composed of the SubSeries listed below.

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