Ontology highlight
ABSTRACT:
SUBMITTER: DeRosa BA
PROVIDER: S-EPMC4278654 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
DeRosa Brooke A BA Van Baaren Jessica M JM Dubey Gaurav K GK Lee Joycelyn M JM Cuccaro Michael L ML Vance Jeffery M JM Pericak-Vance Margaret A MA Dykxhoorn Derek M DM
Neuroscience letters 20120307 1
Induced pluripotent stem cells (iPSCs) hold tremendous potential both as a biological tool to uncover the pathophysiology of disease by creating relevant cell models and as a source of stem cells for cell-based therapeutic applications. Typically, iPSCs have been derived by the transgenic overexpression of transcription factors associated with progenitor cell or stem cell function in fibroblasts derived from skin biopsies. However, the need for skin punch biopsies to derive fibroblasts for repro ...[more]