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Molecular characterization and phylogenetic study of newcastle disease virus isolates from recent outbreaks in eastern Uganda.


ABSTRACT: Newcastle disease virus isolates from chickens in eastern Uganda in 2001 were found to be velogenic by fusion protein cleavage site sequence analysis and biological characterization; the intracerebral pathogenicity index was 1.8. Analysis of their hemagglutinin-neuraminidase protein gene sequences revealed a novel genotype unrelated to those that caused previous outbreaks.

SUBMITTER: Otim MO 

PROVIDER: S-EPMC427882 | biostudies-literature | 2004 Jun

REPOSITORIES: biostudies-literature

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Molecular characterization and phylogenetic study of newcastle disease virus isolates from recent outbreaks in eastern Uganda.

Otim Maxwell O MO   Christensen Henrik H   Jørgensen Poul H PH   Handberg Kurt J KJ   Bisgaard Magne M  

Journal of clinical microbiology 20040601 6


Newcastle disease virus isolates from chickens in eastern Uganda in 2001 were found to be velogenic by fusion protein cleavage site sequence analysis and biological characterization; the intracerebral pathogenicity index was 1.8. Analysis of their hemagglutinin-neuraminidase protein gene sequences revealed a novel genotype unrelated to those that caused previous outbreaks. ...[more]

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