Ontology highlight
ABSTRACT:
SUBMITTER: Mason TA
PROVIDER: S-EPMC4279805 | biostudies-literature | 2014 Jul-Sep
REPOSITORIES: biostudies-literature
Mason Twila A TA Goldenring James R JR Kolobova Elena E
Cellular logistics 20140703 3
Mitochondria regulate metabolism and homeostasis within cells. Mitochondria are also very dynamic organelles, constantly undergoing fission and fusion. The importance of maintaining proper mitochondrial dynamics is evident in the various diseases associated with defects in these processes. Protein kinase A (PKA) is a key regulator of mitochondrial dynamics. PKA is spatially regulated by A-Kinase Anchoring Proteins (AKAPs). We completed cloning of a novel AKAP350 isoform, AKAP350C. Immunostaining ...[more]