Ontology highlight
ABSTRACT:
SUBMITTER: Lee N
PROVIDER: S-EPMC4281345 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
BMB reports 20141101 11
Neutrophils play an important role in the initiation of innate immunity against infection and injury. Although many different types of G-protein coupled receptors are functionally expressed in neutrophils, no reports have demonstrated functional expression of umami taste receptor in these cells. We observed that mouse neutrophils express the umami taste receptor T1R1/T1R3 through RNA sequencing and quantitative RT-PCR analysis. Stimulation of mouse neutrophils with L-alanine or L-serine, which a ...[more]