Ontology highlight
ABSTRACT:
SUBMITTER: Treusch S
PROVIDER: S-EPMC4287466 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Treusch Sebastian S Albert Frank W FW Bloom Joshua S JS Kotenko Iulia E IE Kruglyak Leonid L
PLoS genetics 20150108 1
Signaling pathways enable cells to sense and respond to their environment. Many cellular signaling strategies are conserved from fungi to humans, yet their activity and phenotypic consequences can vary extensively among individuals within a species. A systematic assessment of the impact of naturally occurring genetic variation on signaling pathways remains to be conducted. In S. cerevisiae, both response and resistance to stressors that activate signaling pathways differ between diverse isolates ...[more]