Ontology highlight
ABSTRACT:
SUBMITTER: Spain SL
PROVIDER: S-EPMC4572002 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Human molecular genetics 20150708 R1
Genome-wide association studies (GWAS) have identified thousands of robust and replicable genetic associations for complex disease. However, the identification of the causal variants that underlie these associations has been more difficult. This problem of fine-mapping association signals predates GWAS, but the last few years have seen a surge of studies aimed at pinpointing causal variants using both statistical evidence from large association data sets and functional annotations of genetic var ...[more]