Whole-genome sequencing confirms that Burkholderia pseudomallei multilocus sequence types common to both Cambodia and Australia are due to homoplasy.
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ABSTRACT:
SUBMITTER: De Smet B
PROVIDER: S-EPMC4290968 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
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Whole-genome sequencing confirms that Burkholderia pseudomallei multilocus sequence types common to both Cambodia and Australia are due to homoplasy.
De Smet Birgit B Sarovich Derek S DS Price Erin P EP Mayo Mark M Theobald Vanessa V Kham Chun C Heng Seiha S Thong Phe P Holden Matthew T G MT Parkhill Julian J Peacock Sharon J SJ Spratt Brian G BG Jacobs Jan A JA Vandamme Peter P Currie Bart J BJ
Journal of clinical microbiology 20141112 1
Burkholderia pseudomallei isolates with shared multilocus sequence types (STs) have not been isolated from different continents. We identified two STs shared between Australia and Cambodia. Whole-genome analysis revealed substantial diversity within STs, correctly identified the Asian or Australian origin, and confirmed that these shared STs were due to homoplasy. ...[more]
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