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Avoiding weight gain in cardiometabolic disease: a systematic review.


ABSTRACT: Patients with cardiometabolic disease are at higher risk for obesity-related adverse effects. Even without weight loss, weight maintenance may be beneficial. We performed a systematic review to identify the effect of nonweight loss-focused lifestyle interventions in adults with cardiometabolic disease. We searched MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials to identify comparative studies of lifestyle interventions (self-management, diet, exercise, or their combination) without a weight loss focus in adults with or at risk for diabetes and cardiovascular disease. Weight, BMI, and waist circumference at ?12 months were the primary outcomes. Of 24,870 citations, we included 12 trials (self-management, n = 2; diet, n = 2; exercise, n = 2; combination, n = 6) studying 4,206 participants. Self-management plus physical activity ± diet versus minimal/no intervention avoided meaningful weight (-0.65 to -1.3?kg) and BMI (-0.4 to -0.7?kg/m(2)) increases. Self-management and/or physical activity prevented meaningful waist circumference increases versus control (-2 to -4?cm). In patients with cardiometabolic disease, self-management plus exercise may prevent weight and BMI increases and self-management and/or exercise may prevent waist circumference increases versus minimal/no intervention. Future studies should confirm these findings and evaluate additional risk factors and clinical outcomes.

SUBMITTER: Maruthur NM 

PROVIDER: S-EPMC4291140 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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Avoiding weight gain in cardiometabolic disease: a systematic review.

Maruthur Nisa M NM   Gudzune Kimberly K   Hutfless Susan S   Fawole Oluwakemi A OA   Wilson Renee F RF   Lau Brandyn D BD   Anderson Cheryl A M CA   Bleich Sara N SN   Segal Jodi J  

Journal of obesity 20141228


Patients with cardiometabolic disease are at higher risk for obesity-related adverse effects. Even without weight loss, weight maintenance may be beneficial. We performed a systematic review to identify the effect of nonweight loss-focused lifestyle interventions in adults with cardiometabolic disease. We searched MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials to identify comparative studies of lifestyle interventions (self-management, diet, exercise, or their combinatio  ...[more]

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