Ontology highlight
ABSTRACT:
SUBMITTER: Morita R
PROVIDER: S-EPMC4291653 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Morita Rimpei R Suzuki Mayu M Kasahara Hidenori H Shimizu Nana N Shichita Takashi T Sekiya Takashi T Kimura Akihiro A Sasaki Ken-ichiro K Yasukawa Hideo H Yoshimura Akihiko A
Proceedings of the National Academy of Sciences of the United States of America 20141224 1
Transplantation of endothelial cells (ECs) is a promising therapeutic approach for ischemic disorders. In addition, the generation of ECs has become increasingly important for providing vascular plexus to regenerated organs, such as the liver. Although many attempts have been made to generate ECs from pluripotent stem cells and nonvascular cells, the minimum number of transcription factors that specialize in directly inducing vascular ECs remains undefined. Here, by screening 18 transcription fa ...[more]