Ontology highlight
ABSTRACT:
SUBMITTER: Mitchell RA
PROVIDER: S-EPMC4293307 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Mitchell Robert A RA Yaddanapudi Kavitha K
Cellular signalling 20140930 12
Solid tumors are composed of a heterogeneous population of cells that interact with each other and with soluble and insoluble factors that, when combined, strongly influence the relative proliferation, differentiation, motility, matrix remodeling, metabolism and microvessel density of malignant lesions. One family of soluble factors that is becoming increasingly associated with pro-tumoral phenotypes within tumor microenvironments is that of the migration inhibitory factor family which includes ...[more]