Ontology highlight
ABSTRACT:
SUBMITTER: Brandon MP
PROVIDER: S-EPMC4294702 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Brandon Mark P MP Koenig Julie J Leutgeb Jill K JK Leutgeb Stefan S
Neuron 20140501 4
The hippocampus generates distinct neural codes to disambiguate similar experiences, a process thought to underlie episodic memory function. Entorhinal grid cells provide a prominent spatial signal to hippocampus, and changes in their firing pattern could thus generate a distinct spatial code in each context. We examined whether we would preclude the emergence of new spatial representations in a novel environment during muscimol inactivation of the medial septal area, a manipulation known to dis ...[more]