Ontology highlight
ABSTRACT:
SUBMITTER: Clark NJ
PROVIDER: S-EPMC4295769 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Journal of molecular modeling 20140606 6
Bacterial conjugation, a DNA transfer mechanism involving transport of one plasmid strand from donor to recipient, is driven by plasmid-encoded proteins. The F TraI protein nicks one F plasmid strand, separates cut and uncut strands, and pilots the cut strand through a secretion pore into the recipient. TraI is a modular protein with identifiable nickase, ssDNA-binding, helicase and protein-protein interaction domains. While domain structures corresponding to roughly 1/3 of TraI have been determ ...[more]