Ontology highlight
ABSTRACT:
SUBMITTER: Wang JT
PROVIDER: S-EPMC4296509 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
eLife 20141223
RNA granules have been likened to liquid droplets whose dynamics depend on the controlled dissolution and condensation of internal components. The molecules and reactions that drive these dynamics in vivo are not well understood. In this study, we present evidence that a group of intrinsically disordered, serine-rich proteins regulate the dynamics of P granules in C. elegans embryos. The MEG (maternal-effect germline defective) proteins are germ plasm components that are required redundantly for ...[more]