Ontology highlight
ABSTRACT:
SUBMITTER: Mannel DS
PROVIDER: S-EPMC4299400 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Mannel David S DS Stahl Shannon S SS Root Thatcher W TW
Organic process research & development 20140923 11
Ru(OH) <sub><i>x</i></sub> /Al<sub>2</sub>O<sub>3</sub> is among the more versatile catalysts for aerobic alcohol oxidation and dehydrogenation of nitrogen heterocycles. Here, we describe the translation of batch reactions to a continuous-flow method that enables high steady-state conversion and single-pass yields in the oxidation of benzylic alcohols and dehydrogenation of indoline. A dilute source of O<sub>2</sub> (8% in N<sub>2</sub>) was used to ensure that the reaction mixture, which employ ...[more]