Ontology highlight
ABSTRACT:
SUBMITTER: Lamba P
PROVIDER: S-EPMC4303071 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Lamba Pallavi P Bilodeau-Wentworth Diana D Emery Patrick P Zhang Yong Y
Cell reports 20140417 3
Light is a crucial input for circadian clocks. In Drosophila, short light exposure can robustly shift the phase of circadian behavior. The model for this resetting posits that circadian photoreception is cell autonomous: CRYPTOCHROME senses light, binds to TIMELESS (TIM), and promotes its degradation, which is mediated by JETLAG (JET). However, it was recently proposed that interactions between circadian neurons are also required for phase resetting. We identify two groups of neurons critical fo ...[more]