Morning and Evening Circadian Pacemakers Independently Drive Premotor Centers via a Specific Dopamine Relay.
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ABSTRACT:
SUBMITTER: Liang X
PROVIDER: S-EPMC6533154 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Publications
Morning and Evening Circadian Pacemakers Independently Drive Premotor Centers via a Specific Dopamine Relay.
Liang Xitong X Ho Margaret C W MCW Zhang Yajun Y Li Yulong Y Wu Mark N MN Holy Timothy E TE Taghert Paul H PH
Neuron 20190410 4
Many animals exhibit morning and evening peaks of locomotor behavior. In Drosophila, two corresponding circadian neural oscillators-M (morning) cells and E (evening) cells-exhibit a corresponding morning or evening neural activity peak. Yet we know little of the neural circuitry by which distinct circadian oscillators produce specific outputs to precisely control behavioral episodes. Here, we show that ring neurons of the ellipsoid body (EB-RNs) display spontaneous morning and evening neural act ...[more]
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