Oxygen levels in thermoplastic microfluidic devices during cell culture.
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ABSTRACT:
SUBMITTER: Ochs CJ
PROVIDER: S-EPMC4305448 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Publications
Oxygen levels in thermoplastic microfluidic devices during cell culture.
Ochs Christopher J CJ Kasuya Junichi J Pavesi Andrea A Kamm Roger D RD
Lab on a chip 20140201 3
We developed a computational model to predict oxygen levels in microfluidic plastic devices during cell culture. This model is based on experimental evaluation of oxygen levels. Conditions are determined that provide adequate oxygen supply to two cell types, hepatocytes and endothelial cells, either by diffusion through the plastic device, or by supplying a low flow rate of medium. ...[more]
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