Ontology highlight
ABSTRACT:
SUBMITTER: White JD
PROVIDER: S-EPMC4308504 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
White James D JD Wang Siran S Weiss Anthony S AS Kaplan David L DL
Acta biomaterialia 20141204
Peripheral nerve regeneration may be enhanced through the use of biodegradable thin film biomaterials as highly tuned inner nerve conduit liners. Dorsal root ganglion neuron and Schwann cell responses were studied on protein films comprising silk fibroin blended with recombinant human tropoelastin protein. Tropoelastin significantly improved neurite extension and enhanced Schwann cell process length and cell area, while the silk provided a robust biomaterial template. Silk-tropoelastin blends af ...[more]