DupliPHY-Web: a web server for DupliPHY and DupliPHY-ML.
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ABSTRACT: Summary
Gene duplication and loss are important processes in the evolution of gene families. Moreover, growth of families by duplication and retention is an important mechanism by which organisms gain new functions. Therefore the ability to infer the evolutionary histories of families is an important step in understanding the evolution of function. We have recently developed DupliPHY, a software tool to infer gene family histories using parsimony and maximum likelihood. Here, we present DupliPHY-Web a web server for DupliPHY that implements additional maximum likelihood functionality and provides users an intuitive interface to run DupliPHY.Availability and implementation
DupliPHY-Web is available at www.bioinf.manchester.ac.uk/dupliphy/Contact
: ryan.ames@manchester.ac.ukSupplementary information
Supplementary data are available at Bioinformatics online.
SUBMITTER: Ames RM
PROVIDER: S-EPMC4308661 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Publications
DupliPHY-Web: a web server for DupliPHY and DupliPHY-ML.
Ames Ryan M RM Lovell Simon C SC
Bioinformatics (Oxford, England) 20141007 3
<h4>Summary</h4>Gene duplication and loss are important processes in the evolution of gene families. Moreover, growth of families by duplication and retention is an important mechanism by which organisms gain new functions. Therefore the ability to infer the evolutionary histories of families is an important step in understanding the evolution of function. We have recently developed DupliPHY, a software tool to infer gene family histories using parsimony and maximum likelihood. Here, we present ...[more]
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