Capsaicin from chili ( Capsicum spp.) inhibits vascular smooth muscle cell proliferation.
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ABSTRACT:
SUBMITTER: Liu R
PROVIDER: S-EPMC4314658 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Capsaicin from chili ( Capsicum spp.) inhibits vascular smooth muscle cell proliferation.
Liu Rongxia R Heiss Elke H EH Guo Dean D Dirsch Verena M VM Atanasov Atanas G AG
F1000Research 20150127
Accelerated vascular smooth muscle cell (VSMC) proliferation is implied in cardiovascular disease and significantly contributes to vessel lumen reduction following surgical interventions such as percutaneous transluminal coronary angioplasty or bypass surgery. Therefore, identification and characterization of compounds and mechanisms able to counteract VSMC proliferation is of potential therapeutic relevance. This work reveals the anti-proliferative effect of the natural product capsaicin from C ...[more]
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