HIF-1? -1790G>A polymorphism significantly increases the risk of digestive tract cancer: a meta-analysis.
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ABSTRACT:
SUBMITTER: Sun X
PROVIDER: S-EPMC4316108 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Publications
HIF-1α -1790G>A polymorphism significantly increases the risk of digestive tract cancer: a meta-analysis.
Sun Xiao X Liu Ying-Di YD Gao Wei W Shen Shao-Hua SH Li Meng M
World journal of gastroenterology 20150201 5
<h4>Aim</h4>To investigate the association between hypoxia-inducible factor-1α (HIF-1α) polymorphisms (-1772C>T and -1790G>A) and the risk of digestive tract cancer.<h4>Methods</h4>A total of 13 eligible studies were retrieved from PubMed, EMBASE, and the China National Knowledge Infrastructure database. The odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to estimate the strength of the associations.<h4>Results</h4>By pooling the eligible studies, we found that the HIF-1α -1 ...[more]
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