Ontology highlight
ABSTRACT:
SUBMITTER: Prasain N
PROVIDER: S-EPMC4318247 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Prasain Nutan N Lee Man Ryul MR Vemula Sasidhar S Meador Jonathan Luke JL Yoshimoto Momoko M Ferkowicz Michael J MJ Fett Alexa A Gupta Manav M Rapp Brian M BM Saadatzadeh Mohammad Reza MR Ginsberg Michael M Elemento Olivier O Lee Younghee Y Voytik-Harbin Sherry L SL Chung Hyung Min HM Hong Ki Sung KS Reid Emma E O'Neill Christina L CL Medina Reinhold J RJ Stitt Alan W AW Murphy Michael P MP Rafii Shahin S Broxmeyer Hal E HE Yoder Mervin C MC
Nature biotechnology 20141012 11
The ability to differentiate human pluripotent stem cells into endothelial cells with properties of cord-blood endothelial colony-forming cells (CB-ECFCs) may enable the derivation of clinically relevant numbers of highly proliferative blood vessel-forming cells to restore endothelial function in patients with vascular disease. We describe a protocol to convert human induced pluripotent stem cells (hiPSCs) or embryonic stem cells (hESCs) into cells similar to CB-ECFCs at an efficiency of >10(8) ...[more]