Ontology highlight
ABSTRACT:
SUBMITTER: Sun H
PROVIDER: S-EPMC4322641 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Sun Hailiang H Cui Pengfei P Song Yafen Y Qi Yan Y Li Xiaokang X Qi Wenbao W Xu Chenggang C Jiao Peirong P Liao Ming M
Frontiers in microbiology 20150210
H5N1 influenza viruses with high lethality are a continuing threat to humans and poultry. Recently, H5N1 high-pathogenicity avian influenza virus (HPAIV) has been shown to transmit through aerosols between ferrets in lab experiments by acquiring some mutation. This is another deeply aggravated threat of H5N1 HPAIV to humans. To further explore the molecular determinant of H5N1 HPAIV virulence in a mammalian model, we compared the virulence of A/Duck/Guangdong/212/2004 (DK212) and A/Quail/Guangdo ...[more]