Ontology highlight
ABSTRACT:
SUBMITTER: Sun H
PROVIDER: S-EPMC4331702 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Sun Hong H Yang Shuang S Tun Liangliang L Li Yixue Y
BMC bioinformatics 20150121
<h4>Background</h4>Overlapping transcription constitutes a common mechanism for regulating gene expression. A major limitation of the overlapping transcription assays is the lack of high throughput expression data.<h4>Results</h4>We developed a new tool (IAOseq) that is based on reads distributions along the transcribed regions to identify the expression levels of overlapping genes from standard RNA-seq data. Compared with five commonly used quantification methods, IAOseq showed better performan ...[more]