Self-sampling to increase participation in cervical cancer screening: an RCT comparing home mailing, distribution in pharmacies, and recall letter.

ABSTRACT:

Background

We performed a multicentre randomised controlled trial to evaluate the effect on participation in organised screening programmes of a self-sampling device mailed home or picked up at a pharmacy compared with the standard recall letter.

Methods

Women aged 30-64 non-responding to screening invitation were eligible. Response rate to first invitation ranged from 30% to 60% between centres. The control was the standard reminder letter to undergo the test used by the programme (Pap test in three centres and HPV DNA test in three other centres). Home mailing of the self-sampler was preceded by a letter with a leaflet about HPV. The analysis was intention-to-treat.

Results

In all, 14 041 women were randomised and recruited: 5012 in the control arm, 4516 to receive

SUBMITTER: Giorgi Rossi P 

PROVIDER: S-EPMC4333501 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature