Ontology highlight
ABSTRACT:
SUBMITTER: Johnston SC
PROVIDER: S-EPMC4338303 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Johnston Sara C SC Briese Thomas T Bell Todd M TM Pratt William D WD Shamblin Joshua D JD Esham Heather L HL Donnelly Ginger C GC Johnson Joshua C JC Hensley Lisa E LE Lipkin W Ian WI Honko Anna N AN
PloS one 20150223 2
Henipaviruses are implicated in severe and frequently fatal pneumonia and encephalitis in humans. There are no approved vaccines or treatments available for human use, and testing of candidates requires the use of well-characterized animal models that mimic human disease. We performed a comprehensive and statistically-powered evaluation of the African green monkey model to define parameters critical to disease progression and the extent to which they correlate with human disease. African green m ...[more]