GB virus C coinfections in west African Ebola patients.
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ABSTRACT:
SUBMITTER: Lauck M
PROVIDER: S-EPMC4338908 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Publications
GB virus C coinfections in west African Ebola patients.
Lauck Michael M Bailey Adam L AL Andersen Kristian G KG Goldberg Tony L TL Sabeti Pardis C PC O'Connor David H DH
Journal of virology 20141203 4
In 49 patients with known Ebola virus disease outcomes during the ongoing outbreak in Sierra Leone, 13 were coinfected with the immunomodulatory pegivirus GB virus C (GBV-C). Fifty-three percent of these GBV-C(+) patients survived; in contrast, only 22% of GBV-C(-) patients survived. Both survival and GBV-C status were associated with age, with older patients having lower survival rates and intermediate-age patients (21 to 45 years) having the highest rate of GBV-C infection. Understanding the s ...[more]
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