Phylodynamic assessment of intervention strategies for the West African Ebola virus outbreak.
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ABSTRACT:
SUBMITTER: Dellicour S
PROVIDER: S-EPMC5993714 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
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Phylodynamic assessment of intervention strategies for the West African Ebola virus outbreak.
Dellicour Simon S Baele Guy G Dudas Gytis G Faria Nuno R NR Pybus Oliver G OG Suchard Marc A MA Rambaut Andrew A Lemey Philippe P
Nature communications 20180608 1
Genetic analyses have provided important insights into Ebola virus spread during the recent West African outbreak, but their implications for specific intervention scenarios remain unclear. Here, we address this issue using a collection of phylodynamic approaches. We show that long-distance dispersal events were not crucial for epidemic expansion and that preventing viral lineage movement to any given administrative area would, in most cases, have had little impact. However, major urban areas we ...[more]
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