The molecular timeline of a reviving bacterial spore.
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ABSTRACT:
SUBMITTER: Sinai L
PROVIDER: S-EPMC4339302 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Publications
The molecular timeline of a reviving bacterial spore.
Sinai Lior L Rosenberg Alex A Smith Yoav Y Segev Einat E Ben-Yehuda Sigal S
Molecular cell 20150205 4
The bacterial spore can rapidly convert from a dormant to a fully active cell. Here we study this remarkable cellular transition in Bacillus subtilis and reveal the identity of the newly synthesized proteins throughout spore revival. Our analysis uncovers a highly ordered developmental program that correlates with the spore morphological changes and reveals the spatial and temporal molecular events fundamental to reconstruct a cell. As opposed to current knowledge, we found that translation take ...[more]
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