Ontology highlight
ABSTRACT:
SUBMITTER: Satchwell TJ
PROVIDER: S-EPMC4340578 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Satchwell Timothy J TJ Bell Amanda J AJ Pellegrin Stephanie S Kupzig Sabine S Ridgwell Kay K Daniels Geoff G Anstee David J DJ van den Akker Emile E Toye Ashley M AM
Blood 20110428 1
Band 3, the major anion transport protein of human erythrocytes, forms the core of a multiprotein complex in the erythrocyte membrane. Here we studied the spatiotemporal mechanisms of band 3 multiprotein complex assembly during erythropoiesis. Significant pools of intracellular band 3 and Rh-associated glycoprotein (RhAG) were found in the basophilic erythroblast. These intracellular pools decreased in the polychromatic erythroblast, whereas surface expression increased and were lowest in the or ...[more]