Ontology highlight
ABSTRACT:
SUBMITTER: Alderete TL
PROVIDER: S-EPMC4340767 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Alderete Tanya L TL Sattler Fred R FR Richey Joyce M JM Allayee Hooman H Mittelman Steven D SD Sheng Xia X Tucci Jonathan J Gyllenhammer Lauren E LE Grant Edward G EG Goran Michael I MI
Obesity (Silver Spring, Md.) 20150203 3
<h4>Objective</h4>Salsalate treatment has well-known effects on improving glycemia, and the objective of this study was to examine whether the mechanism of this effect was related to changes in adipose tissue.<h4>Methods</h4>A randomized double-blind and placebo-controlled trial in obese Hispanics (18-35 years) was conducted. The intervention consisted of 4 g day(-1) of salsalate (n = 11) versus placebo (n = 13) for 4 weeks. Outcome measures included glycemia, adiposity, ectopic fat, and adipose ...[more]