Ontology highlight
ABSTRACT:
SUBMITTER: Wang Z
PROVIDER: S-EPMC434119 | biostudies-literature | 2004 Jul
REPOSITORIES: biostudies-literature
Wang Zhi Z Ren Lili L Zhao Xingang X Hung Tao T Meng Anming A Wang Jianwei J Chen Ye-Guang YG
Journal of virology 20040701 14
Severe acute respiratory syndrome (SARS) is an acute respiratory infectious disease that spread worldwide in early 2003. The cause was determined as a novel coronavirus (CoV), SARS-associated CoV (SARS-CoV), with a single-stranded, plus-sense RNA. To date, no effective specific treatment has been identified. To exploit the possibility of using RNA interference as a therapeutic approach to fight the disease, plasmid-mediated small interfering RNAs (siRNAs) were generated to target the SARS-CoV ge ...[more]