Ontology highlight
ABSTRACT:
SUBMITTER: Mallanna SK
PROVIDER: S-EPMC7126941 | biostudies-literature | 2006 Feb
REPOSITORIES: biostudies-literature
Mallanna Sunil Kumar SK Rasool T J TJ Sahay Bikash B Aleyas Abi George AG Ram Hira H Mondal Bimalendu B Nautiyal Binita B Premraj Avinash A Sreekumar E E Yadav M P MP
Virus research 20050930 2
RNA interference (RNAi) mediated by double stranded small interfering RNA (siRNA) is a novel mechanism of post-transcriptional gene silencing. It is projected as a potential tool to inhibit viral replication. In the present paper, we demonstrate the suppression of replication of an avian herpes virus (Anatid Herpes Virus-1, AHV-1) by siRNA mediated gene silencing in avian cells. The UL-6 gene of AHV-1 that codes for a protein involved in viral packaging was targeted. Both cocktail and unique siR ...[more]